Overview

Number of Players
1 (Single Player)
Genre
Release Date

Switch eShop

  • US 6th Feb 2025 — $11.99
  • EU 6th Feb 2025 — £8.09
Official Site
nintendo.com/us/store/products/genome-guar...

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About The Game

COMBINE WEAPONS in the microscopic roguelite turret shooter with macroscopic depth. Survive 6 modes using an astounding array of turrets, perks, mutations and power-ups on this psychedelic journey to the heart of the abyss.

Research permanent upgrades to survive a variety of microbes across 6 game modes, each with multiple "depths".

Pair DNA nucleotides Adenine (rapid fire), Cytosine (precision), Guanine (spread), Thymine (explosive) to discover wild hybrid bioweapons!* Bomb + Shotgun combines explosives with spread to create Blast Shotgun!* Bomb + Bomb doubles down on explosive power to make Bazooka!* Blast Shotgun + Shotgun forms the all-powerful Flak Cannon!

* 49 Turrets with unique strengths and functions* 96 Perks to mix and match that drastically change how you play* 75 Weapon & Turret Mods that can turn shots into sticky laser mines or bouncing fireballs* 64 Mutations alter the challenges you face each run* 20-minute Runs that can be continued in Endless Mode* 75 Bassy Electronic Tunes that adapt to the current mood & intensity* Cosmetics like spider legs and tank tread* Accessibility Settings for color blindness, motion sickness, and even arachnophobia!